INTESTINAL PERMEABILITY/LEAKY GUT TEST

A comprehensive test to assess the integrity of the gut lining. 


What is leaky gut?

The intestines are designed to allow completely digested food particles to pass through the gut wall into the bloodstream. If there is breakdown in the gut barrier (a leaky gut), large food particles and antigens can be allowed to leak into the bloodstream.

A leaky gut has been associated with several gastrointestinal and systemic conditions such as irritable bowel syndrome, irritable bowel disease, autoimmune conditions and neurological conditions.

Food intolerances, gastrointestinal symptoms such as gas and bloating, skin issues and joint pains can often indicate a leaky gut.

Speak to your nutritional practitioner to see if this test would be beneficial for you.


What's the difference between this test and other leaky gut tests?

This test assesses several different markers that helps your practitioner to guide treatment protocols according to which part of the gut lining is affected. 

The test looks at:
Intestinal epithelial cell damage
Intestinal tight junction damage
Gut dysbiosis
Systemic lipopolysaccharides


Scientifically..

The lab will test for antibodies to:

Actomycin - a network of intracellular muscle fibres that bind the cells together. 

Occludin and Zonulin - proteins found on tight junctions inbetween cells.

Lipopolysaccharides - Endotoxins founds on the outer membrane of gram negative bacteria. These are usually present in the gut and not in the bloodstream. However if there is leaky gut or other issues, lipopolysaccharides can leak from the gut into the bloodstream triggering the release of antibodies against them. Accumulation of lipopolysaccharides can have a part to play in numerous chronic conditions.


Pricing - includes private blood test (when applicable) at the clinic worth £50